The ParkMOVE project is a large multidisciplinary project led by Prof. Dr. Erika Franzén at the Karolinska Institutet with the ultimate aim to reduce the disease burden and, particularly, the risk of falls as well as increase health-related quality of life by individually tailored training protocols in individuals with Parkinson's disease. To achieve this aim, this project is divided into 4 stages:

Stages 1 to 3 focused on building the groundwork for improving individualized tailoring of training on the basis of the exploration of motor-cognitive performance between young adults, older adults, and individuals with PD (stage 1), classification of PD subtypes (stage 2), and characterization of predictors for (non-)responders to the HiBalance training in PD (stage 3). 

My responsibility is to coordinate Stage 4 of the projects which builds on the findings of these three previous stages and aims to iteratively co-design, purpose-develop, test, refine, and evaluate a novel hybrid exergame-based motor-cognitive training concept for the secondary/tertiary prevention of PD. The focus of the projects is to develop a training concept that is personalized based on multimodal data to inform decision making on the type, content, and characteristics of the training and is individually tailored and progressed according to real-time physiological and performance data.

Based on our experience and key learnings from previous projects, we are currently working with leading researchers in the field to develop a consensus-based refined methodological guideline for the iterative Co-design, purpose-Development, and evaluation of Individually tailored Technology-enhanced Training concepts (Co-Develop-IT^2) including a checklist to facilitate the effective implementation and reporting of these guidelines. 

The Co-Develop-IT^2 guideline is being developed through hybrid meetings of all involved collaborators every two weeks between August 2024 and February 2025 combined with written elaboration, feedback, and revisions between the meetings, in order to gradually develop a consensus on the individual methodological steps and recommendations as well as the checklist for the effective implementation of these guidelines. 

The proposed methodological guideline will be an extension of the MIDE - Framework [1] and integrates the guidelines of the Medical Research Council for the development and evaluation of complex interventions [2], aspects to inform the design of new technologies from the nonadoption, abandonment, scale-up, spread, and sustainability (NASSS) framework [3], as well as our learnings from previous projects (e.g., [4, 5]). This ensures that all relevant iterative steps based on an interactive and participatory design approach are followed. It also ensures adequate and effective patient and public involvement (PPI) throughout the project and facilitates implementation, scalability, and sustainability of the solutions to be developed. 

Stage 4 of the ParkMOVE project will implement these guidelines. We will provide a step-by-step application example in the manuscript presenting the Co-Develop-IT^2 guideline and provide more information here once it is published.